Tamara Dobson stars as Cleopatra Jones in Jack Starrett's blaxploitation programmer that, in its own way, deals effectively with the ravages of drugs in inner-city black communities. Cleopatra Jones is a jive female James Bond, a special drug agent for the United States government who wears sleek and hip clothes, drives a fancy car with a submachine-gun compartment in the front door, and travels all over the world to stomp out drugs at their source. Cleopatra has a loving relationship with Ruben (Bernie Casey), the well-meaning head of a drug rehabilitation clinic in Los Angeles. When Cleopatra travels to Turkey to oversee the destruction of poppy fields owned by Mommy (Shelley Winters) -- a lesbian drug dealer -- Mommy becomes upset. She exacts her revenge on Cleopatra by having the police close down Ruben's drug clinic. Nevertheless, Cleopatra continues to wreak havoc upon Mommy's drug business, and Mommy continues to try to do Cleopatra in, until finally there is a major confrontation between Cleopatra and Mommy and her minions.