This authoritative clinical reference provides comprehensive coverage of all aspects of rheumatoid arthritis. The basics of rheumatoid arthritis are thoroughly covered in order to provide a firm foundation for the main focus of the text: therapy and clinical management of the disease. Practitioners will find detailed information on both pharmacologic and nonpharmacologic courses of management, with special emphasis on the management of pain. More than 100 full-color illustrations provide clear visual support for the concepts in the text. Online references in each chapter, as well as an entire chapter on Web-based information resources, keep this book on the cutting edge of this rapidly evolving field.

Product Details

ISBN-13: 9780781741491
Publisher: Lippincott Williams & Wilkins
Publication date: 06/23/2004
Pages: 576
Product dimensions: 8.66(w) x 11.10(h) x 1.21(d)

Table of Contents

    Section I. Clinical, Laboratory, and Radiological Features Epidemiology

  1. Clinical Features and Differential Diagnosis
  2. Prognosis and Clinical Course
  3. Clinical and Laboratory Measures of Disease
  4. Diagnostic Autoantibodies
  5. Plain Radiography
  6. Measurement of Radiological Outcomes
  7. Ultrasonography and MRI

    Section III. Section II. Pathogenesis

  8. Genetics
  9. Overview of Pathogenesis
  10. Leukocyte Recruitment and Angiogenesis
  11. Neutrophils and Inflammation
  12. Autoimmunity
  13. Synoviocyte Proliferation
  14. Bone and Cartilage Destruction
  15. The Role of T Cells
  16. Animal Models

    Section IV. Therapy

  17. Approach to Therapy
  18. NSAIDS and Analgesics
  19. Corticosteroids (Systemic and Intra-articular)
  20. Methotrexate and Azathioprine
  21. Sulfasalazine
  22. Gold Compounds, Hydroxychloroquine, D-Penicilamine and Bucillamine
  23. Minocycline
  24. Cyclosporine
  25. Leflunomide
  26. Infliximab and Adalimumab
  27. Etanercept
  28. Anakinra
  29. Staphylococcal Protein A
  30. Combination DMARD Therapy
  31. Treatment of Early Disease

    Section V. Non-Pharmacologic Therapy

  32. Behavioral Therapy
  33. Surgery Total Joint Arthroplasty
    Hand and Wrist Surgery
    Foot and Ankle Surgery
    Cervical Spine Surgery
  34. Special Management Issues Treatment of Extra-Articular Disease
    Web-based Resources for Continuing Education

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