The Synaptic Organization of the Brain

The Synaptic Organization of the Brain

by Gordon M. Shepherd

Paperback(2d ed.)

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It is widely recognized that the neural basis of brain function can be fully understood only by integrating many disciplines at many levels. Studies of synaptic organization are bringing about a quiet revolution in achieving this goal, as documented by this unique book over the past 30 years. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Molecular biologists interested in functional genomics and proteomics of the brain will find answers here to the critical questions: what are the cell and circuit functions of gene products? Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioral and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioral data in authoritative integrated accounts. The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviors. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behavior.

Product Details

ISBN-13: 9780195025491
Publisher: Oxford University Press, USA
Publication date: 08/23/1979
Edition description: 2d ed.
Pages: 338
Product dimensions: 0.00(w) x 0.00(h) x 0.00(d)

About the Author

About the editor
Gordon M. Shepherd, M.D., D. Phil., is Professor of Neuroscience at Yale University School of Medicine. His other books include Neurobiology (3rd ed., 1994) and Foundations of the Neuron Doctrine (1991).

Table of Contents

1. Introduction to Synaptic Circuits, Gordon M. Shepherd
2. Membrane Properties and Neurotransmitter Actions, David A. McCormick
3. Spinal Cord: Ventral Horn, Robert E. Burke
4. Cochlear Nucleus, Eric D. Young and Donata Oertel
5. Olfactory Bulb, Gordon M. Shepherd, Wei R. Chen and Charles A. Greer
6. Retina, Peter Sterling and Jonathan B. Demb
7. Cerebellum, Rodolfo R. Llinas, Kerry D. Walton and Eric J. Lang
8. Thalamus, S. Murray Sherman and R.W. Guillery
9. Basal Ganglia, Charles J. Wilson
10. Olfactory Cortex, Kevin R. Neville and Lewis B. Haberly
11. Hippocampus, Daniel Johnston and David G. Amaral
12. Neocortex, Rodney Douglas, Henry Markram and Kevin Martin

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